Your mission :
We are looking for a PostDoc or Senior Scientist to join our team to explore new approaches in diffractive imaging for high-resolution cryo-Electron Microscopy.
Main duties and responsibilities include:
We explore diffractive electron imaging technologies such as 4D-STEM with ptychography or other reconstruction algorithms to improve resolution and contrast in cryo-EM. The target is high-resolution sub-volume averaging from cryo-electron tomography data, collected by 4D-STEM. We develop this on a custom-tailored 300kV Titan Krios that is equipped with a cold-FEG, an RF cavity for GHz pulsing of stroboscopic single electrons, a Cs probe aberration corrector before the sample, autoloader and CETA/Falcon4i, and followed by DECTRIS ARINA hybrid pixel electron detection operated at 120’000 frames per second. This system is controlled by a TVIPS USG and operated under home-built software. Details are described at
doi.org/10.1038/s41467-024-52403-5
Your profile :
Candidates should have experience in electron microscopy, software development and data processing algorithms. A background in physics, biology or related disciplines is suitable.
We offer :
The EPFL ranks among the world’s top scientific universities. Lausanne is a beautiful, vibrant and highly international city on the shores of the scenic Lake Geneva, situated within an Alpine setting in the heart of Europe. English is the main language at the EPFL and in our laboratory, while Lausanne is in the French-speaking part of Switzerland. The position comes with a competitive salary. EPFL is committed to being an equal opportunity employer.
The successful candidate will join a collaborative, international, and diverse research team with interdisciplinary expertise in biology, physics, computer science and engineering. The focus of research at our Laboratory of Biological Electron Microscopy (LBEM) in the physics department of the EPFL is on neurodegeneration and method development in cryo-EM. We enjoy unique state-of-the-art instrumentation.
More information about our research group can be found at lbem.ch
This position is ERC funded and is available immediately. The start date is flexible.
The position is annually renewable for at least 4 years.
If interested, please contact Henning Stahlberg for more info.