Marta Di Fabrizio

About

Marta joined the LBEM in May 2021 and is now doing her PhD in Neuroscience working on the involvement of axonal damage across synucleinopathies (PD, DLB, MSA). More specifically, she studies the ultrastructure of human myelinated axons with room-temperature electron microscopy both in the peripheral and central nervous systems. Next to this, she is also establishing a workflow to extract alpha-synuclein fibrils from PD human brain using the cryoWriter for structural determination with cryo-EM. Before joining the LBEM, during her Bachelor and Master degrees, she studied Physics at University of Rome ‘La Sapienza’.

Current Project

Ultrastructural study of myelin sheaths in PNS and CNS with room-temperature electron microscopy

Extraction of alpha-synuclein fibrils from the human brain with the cryoWriter

Biography

10.2020 - 01.2021Fellowship at “Terahertz Sapienza” Laboratory - University of Rome ‘La Sapienza’, Italy
10.2017 - 01.2020MSc in Physics, University of Rome ‘La Sapienza’, Italy (Master thesis: “Terahertz time domain spectroscopy and imaging: apparatus development and performances”)
10.2014 - 10.2017BSc in Physics, University of Rome ‘La Sapienza’, Italy

Publications

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Distinct ultrastructural phenotypes of glial and neuronal ...

Böing, C., Di Fabrizio, M., Burger, D., Bol, J.G.J., Huisman, E., Rozemuller, A.J.M., van de Berg, W.D.J., Stahlberg, H., Lewis, A.

(submitted), (2024)

2

FTLD-TDP assemblies seed neoaggregates with subtype-specific features via a prion-like cascade

De Rossi, P., Lewis, A., Furrer, J., De Vos, L., Demeter, T., Zbinden, A., Zhong, W., Wiersma, V.I., Scialo, C., Weber, J., Guo, Z., Scaramuzza, S., Di Fabrizio, M., Böing, C., Castano-Diez, D., Al-Amoudi, A., Pérez-Berlanga, M., Lashley, T., Stahlberg, H., Polymenidou, M.

EMBO Rep. 22(12), e53877 (2021)

PubMed

1