Meltem Tatli

About

Meltem Tatli embarked on her journey in the molecular biology and genetics field at Istanbul Technical University, where her passion for exploring the unknowns of the natural world first took root. During her time in Osaka, as part of Keiichi Namba's research group, she became aware of the revolutionary potential of cryo-EM, an emerging technology that is transforming microscopic studies. Her Ph.D. studies in Zurich under Ohad Medalia's mentorship saw her pushing the limits of what cryo-ET can accomplish, as she investigated the intricate structures of cellulose-degrading enzymes and nucleoskeletal lamins.

Currently, she is exploring a new frontier in her research using cryo-correlative light and electron microscopy (cryo-CLEM) to study neurodegenerative diseases in the post-mortem human brain. Her long-standing interest in understanding the inner workings of the most complex organ in the body, the human brain, and comprehending how diseases can hinder its vital functions fuels her research endeavors.

Current Project

Developing cryo-CLEM pipeline to investigate neurodegenerative diseases in the human brain.

Biography

2022 - presentPostdoc fellow, Laboratory of Biological Electron Microscopy (LBEM), EPFL, Lausanne, Switzerland.
2017 - 2022Ph.D. in Molecular Life Sciences, University of Zurich, Zurich, Switzerland