Alexandra Graff

Former Members

Alexandra Graff

About

Current Project

Biography

Publications
-+

DuoMab: a novel CrossMab-based IgG-derived antibody format for enhanced antibody-dependent cell-mediated cytotoxicity

Sustmann, C., Dickopf, S., Regula, J.T., Kettenberger, H., Mølhøj, M., Gassner, C., Weininger, D., Fenn, S., Manigold, T., Kling, L., Künkele, K.P., Schwaiger, M., Bossenmaier, B., Griese, J.J., Hopfner, K.P., Graff, A., Stahlberg, H., Ringler, P., Lauer, M.E., Brinkmann, U., Schaefer, W., Klein, C.

MAbs 11(8), 1402-1414 (2019)

PubMed

DOI: DOI

Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes

Shahmoradian, S., Lewis, A., Genoud, C., Graff, A., Pérez Navarro, P., Goldie, K., Sütterlin, R., Castano-Diez, D., Ingrassia, A., Rozemuller, A.J.M., Paepe, A.D., Erny, J.Staempfli, A., Hoernschemeyer, J., Niedieker, D., El-Mashtoly, S.F., Gerwert, K., Bohrmann, B., Britschgi, M., Stahlberg, H., van de Berg, W.D.J., Lauer, M.E.

Nature Neuroscience 22, 1099-1109 (2019)

PubMed

DOI: Nature Neurosc.

Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles

Pérez Navarro, P., Genoud, C., Castano-Diez, D., Graff, A., Lewis, A., de Gier, Y., Lauer, M.E., Britschgi, M., Bohrmann, B., Frank, S., Hench, J., Schweighauser, G., Rozemuller, A.J.M., van de Berg, W.D.J., Stahlberg, H., Shahmoradian, S.

Scientific Reports 8(18046), (2018)

DOI: DOI

Characterization of mAb dimers reveals predominant dimer forms common in therapeutic mAbs

Plath, F., Ringler, P., Graff, A., Stahlberg, H., Lauer, M., Rufer, A., Graewert, M., Svergun, D., Kellermann, G., Winkler, C., Stücke, J.O., Koulov, A., Schnaible, V.

mAbs 8(5), 928-940 (2016)

PubMed

DOI:

Cholesteryl ester transfer between lipoproteins does not require the formation of a ternary tunnel complex with the cholesteryl ester transfer protein

Lauer, M.E., Graff, A., Rufer, A.C., Maugeais, C., von der Mark, E., Matile, H., D'Arcy, B., Magg, C., Ringler, P., Müller, S., Scherer, S., Dernick, G., Thoma, R., Hennig, M., Niesor, E.J., Stahlberg, H.

J. Struct. Biol. 194(2), 191-198 (2016)

DOI: 10.1016/j.jsb.2016.02.016

The structure of the mouse serotonin 5-HT3 receptor in lipid vesicles

Kudryashev, M., Castano-Diez, D., Deluz, C., Hassaine, G., Grasso, L., Graff, A., Vogel, H., Stahlberg, H.

Structure 24(1), 165-170 (2016)

PubMed

DOI: 10.1016/j.str.2015.11.004

Disease modeling and phenotypic drug screening for diabetic cardiomyopathy using human induced pluripotent stem cells

Drawnel, F. M., Boccardo, S., Prummer, M., Delobel, F., Graff, A., Weber, M., Gerard, R., Badi, L., Kam-Thong, T., Bu, L., Jiang, X., Hoflack, J. C., Kiialainen, A., Jeworutzki, E., Aoyama, N., Carlson, C., Burcin, M., Gromo, G., Boehringer, M., Stahlberg, H., Hall, B. J., Magnone, M. C., Kolaj

Cell Rep 9(3), 810-21 (2014)

PubMed

X-ray structure of the mouse serotonin 5-HT3 receptor

Hassaine, G., Deluz, C., Grasso, L., Wyss, R., Tol, M. B., Hovius, R., Graff, A., Stahlberg, H., Tomizaki, T., Desmyter, A., Moreau, C., Li, X. D., Poitevin, F., Vogel, H., Nury, H.

Nature 512(7514), 276-81 (2014)

PubMed

Thermal unfolding of a mammalian pentameric ligand-gated ion channel proceeds at consecutive, distinct steps

Tol, M. B., Deluz, C., Hassaine, G., Graff, A., Stahlberg, H., Vogel, H.

J Biol Chem 288(8), 5756-69 (2013)

PubMed

Structure and function of purified monoclonal antibody dimers induced by different stress conditions

Paul, R., Graff, A., Stahlberg, H., Lauer, M. E., Rufer, A. C., Beck, H., Briguet, A., Schnaible, V., Buckel, T., Boeckle, S.

Pharm Res 29(8), 2047-59 (2012)

PubMed