Massimo Kube

About

Massimo joined the LBEM in February 2024 after doing his PhD in Prof. Hendrik Dietz’s lab in Munich. During his PhD, he worked on the three-dimensional reconstruction of DNA Origami structures. His main project focussed on the development of a DNA Origami force spectrometer that allows for the reconstruction of force-sensitive proteins while a force is applied at the same time.
Continuing his journey of innovation, Massimo has now embarked on a new project at the LBEM. He is currently developing a 4D STEM workflow for biological samples under cryo-EM conditions, a project that promises to push the boundaries imposed by classical CTEM in this field.

Current Project

Development of a 4D STEM pipeline for Cryo-EM.

Biography

Education

2/2024 - presentPostDoc, Laboratory of Biological Electron Micoscopy (LBEM), Institute of Physics, EPFL, Switzerland
1/2023 - 1/2024 PostDoc, Laboratory of Bionanotechnology and Molecular Robotics at the Technical University Munich, Germany
5/2017 - 12/2022PhD Thesis, Laboratory of Bionanotechnology and Molecular Robotics at the Technical University Munich, Germany

Publications

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Low-dose cryo-electron ptychography of proteins at sub-nanometer resolution

Küçükoglu, B., Mohammed, I., Guerrero Ferreira, R., Kube, M., Radecke, J., Ribet, S.M., Varnavides, G., Leidl, M.L., Lau, K., Nazarov, S., Myasnikov, A., Sachse, C., Müller-Caspary, K., Ophus, C., Stahlberg, H.

Nature Communications 15, 8062 (2024)

DOI: DOI

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