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Daniel Castano-Diez

About

Current Project

Biography

Publications

-+

Automated fiducial-based alignment of cryo-electron tomography tilt series in Dynamo

Coray, R., Pérez Navarro, P., Scaramuzza, S., Stahlberg, H., Castano-Diez, D.

Structure 32(10), 1808-1819.e4 (2024)

21

FTLD-TDP assemblies seed neoaggregates with subtype-specific features via a prion-like cascade

De Rossi, P., Lewis, A., Furrer, J., De Vos, L., Demeter, T., Zbinden, A., Zhong, W., Wiersma, V.I., Scialo, C., Weber, J., Guo, Z., Scaramuzza, S., Di Fabrizio, M., Böing, C., Castano-Diez, D., Al-Amoudi, A., Pérez-Berlanga, M., Lashley, T., Stahlberg, H., Polymenidou, M.

EMBO Rep. 22(12), e53877 (2021)

PubMed

20

Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes

Shahmoradian, S., Lewis, A., Genoud, C., Graff, A., Pérez Navarro, P., Goldie, K., Sütterlin, R., Castano-Diez, D., Ingrassia, A., Rozemuller, A.J.M., Paepe, A.D., Erny, J.Staempfli, A., Hoernschemeyer, J., Niedieker, D., El-Mashtoly, S.F., Gerwert, K., Bohrmann, B., Britschgi, M., Stahlberg, H., van de Berg, W.D.J., Lauer, M.E.

Nature Neuroscience 22, 1099-1109 (2019)

PubMed

DOI: Nature Neurosc.

19

‘Differential visual proteomics’: Enabling the proteome-wide comparison of protein structures of single-cells

Syntychaki, A., Rima, L., Schmidli, C., Stohler, T., Bieri, A., Sütterlin, R., Stahlberg, H., Castano-Diez, D., Braun, T.

J. of Proteome Research 18(9), 3521-3531 (2019)

PubMed

DOI: DOI

18

Cerebral Corpora amylacea are dense membranous labyrinths containing structurally preserved cell organelles

Pérez Navarro, P., Genoud, C., Castano-Diez, D., Graff, A., Lewis, A., de Gier, Y., Lauer, M.E., Britschgi, M., Bohrmann, B., Frank, S., Hench, J., Schweighauser, G., Rozemuller, A.J.M., van de Berg, W.D.J., Stahlberg, H., Shahmoradian, S.

Scientific Reports 8(18046), (2018)

DOI: DOI

17

Protocols for Subtomogram Averaging of Membrane Proteins in the Dynamo Software Package

Pérez Navarro, P., Stahlberg, H., Castano-Diez, D.

Frontiers in Molecular Biosciences 5(82), 1-18 (2018)

PubMed

DOI: DOI

16

Demonstration of femtosecond X-ray pump X-ray probe diffraction on protein crystals

Opara, N., Mohacsi, I., Makita, M., Castano-Diez, D., Diaz, A., Jurani, P., Marsh, M., Meents, A., Milne, C.J., Mozzanica, A., Padeste, C., Panneels, V., Sikorski, M., Song, S., Stahlberg, H., Vartiainen, I., Vera, L., Wang, M., Willmott, P.R., David, C.

Structural Dynamics 5(5), 054303 (2018)

PubMed

DOI: DOI

15

CryoEM structure of the extended type VI secretion system sheath–tube complex

Wang, J., Brackmann, M., Castano-Diez, D., Kudryashev, M., Goldie, K., Maier, T., Stahlberg, H., Basler, M.

Nature Microbiology 2(11), 1507-1512 (2017)

PubMed

DOI: DOI

14

Focus: The interface between data collection and data processing in cryo-EM

Biyani, N., Righetto, R., McLeod, R., Caujolle-Bert, D., Castano-Diez, D., Goldie, K., Stahlberg, H.

J. Struct. Biol. 198(2), 124-133 (2017)

PubMed

DOI:

13

Dynamo Catalogue: Geometrical tools and data management for particle picking in subtomogram averaging of cryo-electron tomograms

Castano-Diez, D., Kudryashev, M., Stahlberg, H.

J. Struct. Biol. 197(2), 135-144 (2017)

PubMed

DOI: 10.1016/j.jsb.2016.06.005

12

The structure of the mouse serotonin 5-HT3 receptor in lipid vesicles

Kudryashev, M., Castano-Diez, D., Deluz, C., Hassaine, G., Grasso, L., Graff, A., Vogel, H., Stahlberg, H.

Structure 24(1), 165-170 (2016)

PubMed

DOI: 10.1016/j.str.2015.11.004

11

Automation of image processing in electron crystallography

Arheit, M., Castano-Diez, D., Thierry, R., Gipson, B., Zeng, X., Stahlberg, H.

Methods Mol Biol 955, 313-30 (2013)

PubMed

10

Structure of the dodecameric Yersinia enterocolitica secretin YscC and its trypsin-resistant core

Kowal, J., Chami, M., Ringler, P., Müller, S., Kudryashev, M., Castano-Diez, D., Amstutz, M., Cornelis, G. R., Stahlberg, H., Engel, A.

Structure 21(12), 2152-61 (2013)

PubMed

9

Image processing of 2D crystal images

Arheit, M., Castano-Diez, D., Thierry, R., Gipson, B., Zeng, X., Stahlberg, H.

Methods Mol Biol 955, 171-94 (2013)

PubMed

8

In situ structural analysis of the Yersinia enterocolitica injectisome

Kudryashev, M., Stenta, M., Schmelz, S., Amstutz, M., Wiesand, U., Castano-Diez, D., Degiacomi, M. T., Munnich, S., Bleck, C., Kowal, J., Diepold, A., Heinz, D. W., Dal Peraro, M., Cornelis, G. R., Stahlberg, H.

Elife 2, e00792 (2013)

PubMed

7

Merging of image data in electron crystallography

Arheit, M., Castano-Diez, D., Thierry, R., Abeyrathne, P., Gipson, B., Stahlberg, H.

Methods Mol Biol 955, 195-209 (2013)

PubMed

6

Analysis of 2-D crystals of membrane proteins by electron microscopy

Abeyrathne, P., Arheit, M., Kebbel, F., Castano-Diez, D., Goldie, K., Chami, M., Relault, L., Kühlbrandt, W., Stahlberg, H.

Comprehensive Biophysics 1, 277-310 (2012)

DOI: 10.1016/B978-0-12-374920-8.00119-3

5

Assessing the benefits of focal pair cryo-electron tomography

Kudryashev, M., Stahlberg, H., Castano-Diez, D.

J Struct Biol 178(2), 88-97 (2012)

PubMed

4

Dynamo: a flexible, user-friendly development tool for subtomogram averaging of cryo-EM data in high-performance computing environments

Castano-Diez, D., Kudryashev, M., Arheit, M., Stahlberg, H.

J Struct Biol 178(2), 139-51 (2012)

PubMed

3

Limiting factors in single particle cryo electron tomography

Kudryashev, M., Castano-Diez, D., Stahlberg, H.

Comput Struct Biotechnol J 1, e201207002 (2012)

PubMed

2

3D reconstruction from 2D crystal image and diffraction data

Schenk, A. D., Castano-Diez, D., Gipson, B., Arheit, M., Zeng, X., Stahlberg, H.

Methods Enzymol 482, 101-29 (2010)

PubMed

1

2009-2013 & 2015-2020, Senior Scientist

+41 61 387 32 23

C-CINA, Biozentrum, Uni Basel, Room P.36, Mattenstrasse 26, CH-4058 Basel, Switzerland

daniel.castano@unibas.ch